CD14 is a human membrane glycoprotein that plays an important role in the immune system. It is a receptor that is widely present on the surface of monocytes and macrophages, and is involved in the recognition and response of the immune system to bacteria and pathogens. CD14 typically interacts with Toll-like receptors (TLRs) to regulate the activation of immune cells and inflammatory responses.
Specifications
Catalog Number:
KP-3002
Antibodies Name:
CD14-antibody
Host Cell Line:
EXPI-CHO
Target:
CD14
Species Reactivity:
Human
Application:
ELISA
Purification Method:
Affinity purified
Concentration:
>2mg/mL
Purity:
>95% by SDS-PAGE and SEC-HPLC
Endotoxin Level:
<0.5 EU/mg as determined by the LAL method
Sterility:
0.2μm filtered
Formulation:
20mM sodium citrate,150mM NaCl, pH5.5
Storage:
Stable for twelve months from date of receipt when stored at -20°C to -80°C; Stored at 2-8°C for one month without detectable loss of activity.
Bio Safety Level:
1
Validation:
SDS-PAGE | SEC-HPLC | ELISA
Characterization
Application
References
1.Akashi-Takamura, S., and Miyake, K. (2008). TLR accessory molecules. Curr. Opin. Immunol. 20, 420ÿ425.
2.Baumann, C. L., Aspalter, I. M., Sharif, O., Pichlmair, A., Bluml, S., Grebien, F., et al. (2010). CD14 is a coreceptor of Toll-like receptors 7 and 9. J. Exp. Med. 207, 2689ÿ2701.
