In Vivo Services
Syngeneic Model Overview
In syngeneic tumor models, tumor cells or tissues derived from mice are transplanted into host mice with the same genetic background and immune competence. The resulting allografts (i.e., tumors) formed in syngeneic tumor models are free from rejection reactions due to the consistent genetic background of the tissue donor and transplant recipient. Simultaneously, the syngeneic tumor mouse model eliminates the complex process of immune reconstitution in immunodeficient mice. This advantage of maintaining a complete immune system in mice makes the syngeneic tumor mouse model a powerful tool for studying the tumor microenvironment, tumor metastasis, and, especially, for evaluating immunomodulatory therapies.
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Ba/F3 Xenograft focuses on protein kinases, a cornerstone in cancer research. With FDA’s acknowledgment of kinase drugs, it offers important oncology insights aiding for deeper understanding.
Gene-edited xenografts, utilizing tools like CRISPR/Cas9, offer precise modifications to tumor cell genomes, significantly expanding the horizons and potential of modern oncological research methodologies and insights.
Luciferase tumor model provides insights into tumor growth and immune dynamics. Using bioluminescence, it provides real-time insights. This innovative approach deepens comprehension, advancing cancer research and promoting novel therapeutic discoveries.
PBMC Humanized Mouse Model incorporates human T cells’ behavior, enabling detailed tumor immunology analysis. It presents a unique avenue for in-depth exploration, enriching research and offering a comprehensive study platform.
The Syngeneic Model leverages the uses of mouse-derived tumor tissues, placed into genetically similar hosts, contributing to consistency and depth in cancer studies. Ensures a genuine environment for cancer study.
The Subcutaneous tumor models are a leading choice for evaluating anti-cancer drug efficacy, supporting clinical trials, and understanding potential treatments. Its established method is a key component in therapeutic research.
The subcutaneous tumor model is one of the most commonly used in vivo evaluation systems for assessing the efficacy of novel anti-cancer drugs. Typically, tumor …
The CDX Model utilizes human tumor cells cultured and introduced into immunodeficient mice, providing a distinct perspective in cancer research.This approach offers a unique, in-depth exploration into cancer behaviors.