Membrane Protein Antibody Discovery, MPSA AB5000

De-Risk the off-target interactions of your antibody drug for IND application.

MPSA-AB5000 Introduction

MPSA-AB5000The specificity of antibodies, CAR-T cells, and other biologic therapeutics to their binding targets is an important step in the evaluation process of drug development. The lack of suitable methods to identify the targets of functional antibodies and ligands result in drug safety accidents and the abandonment of previous studies. KYinno’s Membrane Proteins Screening Array (MPSA-AB5000) is an excellent solution for antibody specificity screening which enable early off-target screening and can de-risk the antibody drug development program.

Full Coverage of Human Membrane Protein Library

  • The MPSA-AB5000 makes use of more than 5000 unique human membrane protein, including receptors, transporters, enzymes, miscellaneous, and others.
  • Natively expressed in live cells ensuring native protein conformation.

High Sensitivity Reporter System Detection

  • Wash-free strategy reduces false negatives.
  • Signal amplification makes large discrimination.
  • High throughput microplate system guarantees best stability and creditability.

Compatibility with Different Types of Biologic Therapeutics:

  • MPSA-AB5000 is compatible with monoclonal antibodies, bispecific antibodies, ADC, orphan protein and antibody, as well as CAR-T cell therapies.

Successfully Screened Off-target Molecules

  • Ultrashort turnaround for data report
  • Competitively priced

MPSA-AB5000 is rapid, simple and highly sensitive by measuring binding via reporter cell line and can determine specificity and preclinical safety of biotherapeutics conveniently.

All Antibody Discovery Services

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Hybridoma technology is the bedrock of antibody discovery, merging immunized cells to generate monoclonal antibodies. This ensures consistency, high specificity, and high yield for therapeutic and diagnostic applications.

Single B Cell Screening for Antibody Discovery

Single B cell screening represents a breakthrough in antibody discovery. Using state-of-the-art technology to isolate, sequence, and analyze individual B cells, ensuring precise identification of specific antibodies for novel treatments.

Bispecific Antibodies - Bridging Targets and Effector Molecules

Utilizing advanced biotechnology, our engineered bispecific antibodies bind two distinct targets. This innovation has the potential to revolutionize therapeutic strategies, heightening specificity, expanding treatment options, and paving the way for future medical advancements.

Nanobody Screening
Taking advantage of camelid-derived nanobodies, we present a distinct antibody structure providing exceptional therapeutic versatility. This innovation leads to innovative approaches to treatments and diagnostics and broadens the modern medical solutions.
In silico developability assessment, transforming biomedicine by providing groundbreaking approaches to predicting antibody developability. Leveraging advanced computational insights, streamline research processes, enhance therapeutic product robustness, and accelerate innovative drug discovery.
Methods for humanizing antibodies
With our profound expertise, we optimize antibodies for human compatibility, boosting therapeutic outcomes. Reducing adverse reactions, we lay the groundwork for innovative, patient-focused personalized medicine, customized for each individual.
With the advent of the era of precision medicine, monoclonal antibody drugs have become a hotspot in biological drug treatment due to their high specificity and effectiveness. As the types of monoclonal antibody drugs increase and their applications widen, related immunogenicity issues gradually emerge. For patients, immunogenicity affects the safety and effectiveness of drugs, and even brings fatal new diseases to patients due to ADA and endogenous protein cross-reactivity; for enterprises, the risk of research and development greatly increases, and if ADA problems are discovered in the late stage of clinical development, it will result in heavy losses; for drug regulatory departments, immunogenicity has also become a top priority, and all biological drugs must have an immunogenicity evaluation before they go on the market to ensure the safety and effectiveness of the drugs.
Our comprehensive assessment of drug potential and immune responses guarantees therapeutic safety and efficacy. This rigorous process is vital in bridging the transition from lab research to successful clinical stage implementation.
Using antibodies with high specificity, we guarantee precise binding targets for CAR-T cells and biologics. This meticulous approach is foundational to therapeutic success and patient outcomes. Promoting next-generation healthcare solutions.
GPCR Antibody Screening Expertise
Targeting G-protein coupled receptors, we access an expansive therapeutic domain. Concentrating on these essential proteins, we not only enhance drug efficacy but also pioneer breakthroughs, broadening horizons in modern drug development.
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Nanobodies, featuring high affinity and stability, revolutionize therapeutic approaches. Their unique properties make them invaluable, especially in the areas of targeted drug delivery, advanced diagnostics, and innovative disease intervention strategies.
hybridoma technology - antibody discovery services.docx
KYINNO sets the standard, prioritizing high-quality antibody production. We emphasize unmatched consistency, purity, and reliability, setting industry guidelines, fostering trust, and accelerating groundbreaking drug discovery and innovative research endeavors.
hybridoma technology - antibody discovery services.docx
Bispecific antibodies from KY-CLC bind two distinct antigens, offering advanced therapeutic avenues, enhancing drug delivery, and increasing the potential for successful patient outcomes.
AI Drug Discovery
Nanobodies, known for their small molecular weight, high affinity, stability, permeability, and cost-effectiveness, have demonstrated tremendous potential in disease …