KC-3662
CEACAM6 encodes CEA cell adhesion molecule 6 and is also known as NCA. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
| Catalog Number | KC-3662 |
|---|---|
| Cell Line Name | 293T-CEACAM6 Cell Line |
| Host Cell Line | 293T |
| Description | 293T-CEACAM6 is a stable engineered cell line expressing human CEACAM6 |
| Quantity | One vial of frozen cells (≥2×10⁶ cells/vial) |
| Stability | Stable in culture over a minimum of 10 passages |
| Application | Drug screening and biological assays |
| Freezing Medium | 70% DMEM+20% FBS+10% DMSO |
| Propagation Medium | DMEM+10%FBS+1ug/mL Puromycin |
| Selection Marker | Puromycin |
| Morphology | Epithelial |
| Subculture | Split at a ratio of 1:4–1:6 every 2–3 days |
| Incubation | 37 °C with 5% CO₂ |
| Storage | Liquid nitrogen immediately upon receiving |
| Doubling Time | Estimated 19–36 hours |
| Mycoplasma Status | Negative |
| In Vivo Validation | NA |
Figure 1: Characterization of CEACAM6 overexpression in the 293T CEACAM6 stable clone using FACS.
Figure 2: Characterization of CEACAM6 overexpression in 293T cell using FACS.
