KB-1078

SHR-1210-hIgG1

Background

SHR-1210 is a monoclonal antibody directed against programmed cell death 1 (PD-1), a protein found on the surface of specialized immune system cells called T-cells. When bound to its ligand, the programmed cell death ligand 1 (PD-L1), PD-1 suppresses the immune function of T-cells to ensure that they do not mistakenly attack healthy cells.

Specifications

Catalog Number:
KB-1078
Cell Line Name:
SHR-1210-hIgG1
Price:
0
Host Cell Line:
EXPI-CHO
Target:
PD1
Species Reactivity:
Human
Application:
ELISA
Purification Method:
Affinity purified
Concentration:
>2mg/mL
Purity:
>95% by SDS-PAGE and SEC-HPLC
Endotoxin Level:
<0.5 EU/mg as determined by the LAL method
Sterility:
0.2μm filtered
Formulation:
20mM sodium citrate,150mM NaCl, pH5.5
Storage:
Stable for twelve months from date of receipt when stored at -20°C to -80°C; Stored at 2-8°C for one month without detectable loss of activity.
Bio Safety Level:
1
Validation:
SDS-PAGE | SEC-HPLC | ELISA

References

1.Ajani JA, D'Amico TA, Almhanna K, Bentrem DJ, Besh S, Chao J, et al Esophageal and esophagogastric junction cancers, version 1.2015. J Natl Compr Canc Netw 2015;13:194–227. 2.Ohashi S, Miyamoto S, Kikuchi O, Goto T, Amanuma Y, Muto M. Recent advances from basic and clinical studies of esophageal squamous cell carcinoma. Gastroenterology 2015;149:1700–15. 3.Huang J, Zhou Y, Zhang H, Qu T, Mao Y, Zhu H, et al A phase II study of biweekly paclitaxel and cisplatin chemotherapy for recurrent or metastatic esophageal squamous cell carcinoma: ERCC1 expression predicts response to chemotherapy. Med Oncol 2013;30:343.
Please enable JavaScript in your browser to complete this form.