M2 Macrophages to M1 Polarization Assay
M2 Macrophages to M1 Polarization Assay Overview
M2 and M1 macrophages represent distinct subtypes of macrophages, each characterized by specific functions and secretory factor expression patterns. Reprogramming M2 macrophages into the M1 phenotype offers researchers a valuable tool for investigating their roles in inflammation and immune-related diseases. Moreover, this approach allows for exploration of their potential applications in immunotherapy and drug screening. For instance, the activation of macrophages can be achieved through the use of antibodies targeting molecules such as CD40, IFN-γ receptors, and Toll-like receptors (TLRs).
Kyinno possesses extensive expertise in this field and is equipped with advanced tools and techniques to conduct high-quality M2 to M1 polarization experiments. Our services empower researchers to obtain crucial data concerning the conversion of macrophage subtypes, facilitating a deeper comprehension of their functions and interplay within biological systems. This knowledge contributes significantly to unraveling the mechanisms underpinning immune diseases and inflammation-related disorders. Furthermore, it provides valuable insights for the development of novel drugs and immunotherapeutic strategies.
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