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MLR

MLR

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Description:
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Mixed lymphocyte reaction (MLR) is an ex-vivo cellular immune assay that occurs between two allogeneic lymphocyte populations. The principle of MLR is that T cells from one donor will proliferate in the presence of APCs from a different donor. This is caused by the recognition of an HLA mismatch between two unrelated donors, which provokes an immune response from the T cells. MLR is often used to study the functions of immune-checkpoint antibodies through the measurement of induced IL-2 and IFN-γ expression.  

 

 

 

Assay Specifications:  

T cell and DC donors are pre-screened for their immune reaction. Assays are performed using a 96-well format. Each data point is tested in triplicate, and appropriate assay controls are included.

 

 

Case Study:

 

 

Turn-Around Time

2 - 3 weeks

Timeline & pricing may vary depending on custom assay specifications.

KYinno

 KYinno Biotechnology Co., Ltd

Cell phone No: +(86)10-58222701 / 58222702

Room 609, No.3 Building, Yizhuang Biomedical Park, No.88, Kechuang Six Street, BDA,

 

Beijing, China, 101111

Email: bd@kyinno.com 

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